SRI International expands BioCyc database collection for genomics researchers

By on July 12, 2022 0

BioCyc database reaches 20,000 genomes before collaboration with Wolters Kluwer

MENLO PARK, Calif., July 12, 2022 /PRNewswire/ — SRI International, an independent, not-for-profit research institute, today announced that its BioCyc database collection now exceeds 20,000 organism-centric Pathway/Genome Databases (PGDBs). The collection, which has doubled in the past five years, provides solutions for managing genome and pathway data for multiple industries, including agriculture, bioinformatics, biotechnology, drug discovery, genomics and synthetic biology.

SRI’s BioCyc and Pathway tools provide genome and metabolic pathway information as well as software tools for research, analysis and visualization.

“BioCyc databases are extremely comprehensive, incorporating computational inference, data imported from other databases, and hand-picked information from 130,000 peer-reviewed publications,” said Peter Karp, Director of the SRI Bioinformatics Research Group. “Each database consists of an organism’s annotated genome and its inferred metabolic pathways. Sixty-nine of the BioCyc databases are curated, incorporating detailed information from experimental literature.”

BioCyc and the associated Pathway Tools software have been in continuous development for twenty-five years and are used by scientists, researchers, educators, and students at thousands of colleges, universities, non-profit organizations, government laboratories and commercial enterprises worldwide. MetaCyc is a key database within the BioCyc collection, containing organized information on metabolic reactions, pathways and enzymes. MetaCyc contains 3,006 metabolic pathways, making it one of the largest collections of organized metabolic pathways.

BioCyc was recently integrated with Wolters Kluwer’s Ovid® platform to increase genomics researchers’ access to comprehensive data.

“These large databases will create a one-stop shop for information on genomic and metabolic pathways,” said Vikram Savkar, senior vice president and general manager, medicine segment of the Learning, Research and Practice business in health at Wolters Kluwer. “By adding a direct link to BioCyc’s PGDBs and software tools to Ovid, we’re connecting to a whole new dimension of aggregated data that researchers need to accelerate the pace of their work.

Researchers are encouraged to visit the BioCyc website to create an account. By doing so, they can access two important databases within BioCyc, namely EcoCyc and MetaCyc, free of charge.

To learn more about the BioCyc database and to create a free account, visit the BioCyc website at

About SRI International:

SRI International creates world-changing solutions to make people safer, healthier and more productive. SRI, a research center headquartered in Menlo Park, California, works mainly in advanced technologies and systems, biosciences, IT and education. SRI brings its innovations to market through technology licensing, spin-offs and new product solutions. Visit

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SOURCE SRI International